Pay on our site
up to 10% less
than on Booking.com
Check rooms and rates
From209US$ /night
Check-in
25Jan2026Select date
Check-out
26Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

3A, Calle Oriente N.28, Antigua, Guatemala, 03001
-
Steps from the Central Park
Perfect
9.0
9.2
/10
4.7
4.5
/5

Accommodations

Hotel Museo Spa Casa Santo Domingo offers 134 rooms, including 26 with the concept of SPA Living. Each room is adorned with works of art from renowned local artists, providing a cultural touch to the ambience. Guests may enjoy unique artistic weavings that elevate each stay.

Dining Experience

Guests can experience a culinary journey at El Refectorio, serving international dishes with a Guatemalan touch under the direction of Chef Mario Enrique Campollo. The restaurant also offers a typical Guatemalan afternoon buffet on Saturdays, Sundays, and festive days. Additionally, there is a sushi bar and Bar Cabildo for craft cocktails and fine wines.

Wellness and Spa

The hotel boasts a luxurious spa that includes indoor and outdoor areas, jacuzzis, pools, and saunas. Specialized treatments for body, mind, and spirit are available, designed for both men and women. Guests may also reserve rooms with direct access to the spa for an intimate experience.

Cultural Attractions

Hotel Museo Spa Casa Santo Domingo offers six permanent museums and two art galleries featuring temporary exhibits. Guests can explore the rich cultural heritage of Antigua Guatemala while staying at the hotel. This unique aspect allows for an engaging experience beyond typical accommodations.

Sustainability Practices

The hotel emphasizes sustainability in its operations, from preserving local biodiversity to energy savings. Specific actions reconcile work, family, and personal life for its hosts. Conservation efforts focus on the region's natural areas, promoting responsible tourism.

Highlights

Location: Cultural attractions with six permanent museums and two art galleries

Rooms: 134 rooms, including 26 with spa access

Dining: El Refectorio with refined international dishes

Wellness: Luxurious spa with treatments for body and mind

Sustainability: Conservation efforts focusing on local biodiversity

Must-do experiences

  • Visit the stunning ruins of Convento de las Capuchinas at sunset.
  • Try Pepián, a traditional stew, at Restaurante El Fogón.
  • Take a guided tour of the unique Jade Museum for local culture.
  • Explore the vibrant Artisans Market for handmade Guatemalan crafts.
  • Participate in a chocolate workshop at ChocoMuseo for sweet fun.
View all

Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room Spa Bath
2 persons
510 sq. feet 
1 King-size bed
Fireplace
Air conditioning
Deluxe Double Room
2 persons
510 sq. feet 
2 Double beds
Fireplace
Air conditioning
Standard Double Room
2 persons
380 sq. feet 
2 Double beds
Fireplace
Air conditioning
Deluxe Suite
2 persons
1080 sq. feet 
1 King-size bed
Fireplace
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Free parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Currency exchange
  • ATM/Cash machine
  • Hairdresser
  • Smoke detectors
  • Fire extinguishers
  • Key access

Sports & Fitness

  • Fitness centre

Services

  • Paid airport shuttle
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Outdoor swimming pool
  • Beach umbrellas
  • Sun loungers
  • Sun terrace
  • Garden area
  • Spa & wellness centre
  • Solarium
  • Sauna
  • Steam room
  • Jacuzzi
  • Pedicure
  • Manicure
  • Waxing
  • Body scrub
  • Facial
  • Treatment room
  • Body wraps
  • Back massage
  • Head massage
  • Full body massage
  • Foot massage
  • Open-air bath
  • Make up services

Room features

  • Air conditioning
  • Mini-bar
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
Show more

Dining Onsite

Hotel Museo Spa Casa Santo Domingo offers a delightful array of dining experiences, combining international cuisine with enchanting settings that evoke the rich culture surrounding you. Guests can enjoy cozy meals in serene environments that showcase the artistry of local flavors and culinary traditions.

El Tenedor

International Breakfast and Traditional Cuisine
Ambiance
A warm and inviting space that welcomes guests with artistic decor, where the sounds of nature blend seamlessly with the culinary offerings.
Key Offerings
Delicious breakfasts and traditional dishes reflect both global and local influences, perfect for starting the day or enjoying a hearty meal.
Reservation
No
07:00 - 22:00, daily

Tenedor del Cerro

International Cuisine with Nature and Culture elements
Ambiance
Nestled in a picturesque setting surrounded by lush greenery, this restaurant captures the beauty of its natural surroundings while offering a cozy dining experience.
Key Offerings
A variety of lite options featuring classic oriental cuisine interwoven with national touches, ideal for those seeking something light yet flavorful.
Reservation
No
07:00 - 22:00, daily

El Cabido

Snacks and Refreshments
Ambiance
A charming terrace that encourages relaxation, where guests can unwind with their favorite drink in a delightful atmosphere.
Key Offerings
Light snacks and refreshing beverages, featuring a cozy space perfect for sharing moments with friends, partners, or colleagues.
Reservation
No
Open daily, specific hours vary

Location

3A, Calle Oriente N.28, Antigua, Guatemala, 03001
Map view
3A, Calle Oriente N.28, Antigua, Guatemala, 03001
Nearby
3a Calle Oriente 28
Casa Santo Domingo Museums
1700 ft
4a Calle Oriente # 14 15C
ChocoMuseo
1600 ft
5a Calle Poniente
Palace of the Captain Generals
1100 ft
2a Avenida Norte y 2a Calle Oriente esquina. Antigua Guatemala
Convento de las Capuchinas
1600 ft
6a Calle Oriente
Tanque La Union
1000 ft
4 Calle Oriente # 10 Edificio El Jaulon
Casa del Jade
500 ft
Museum
Casa Popenoe
1400 ft
Avenida 1a
Paseo De Los Museos
100 ft
Museum
Casa Santo Domingo
1100 ft
Square
Antigua Guatemala
2000 ft
Church
Iglesia El Carmen
1400 ft
Museum
Antigua Guatemala Colonial Art Museum
1900 ft
Store
La bodegona
1300 ft
cnr 3a Calle Oriente & 3a Av Norte
Mercado de Artesanias El Carmen
1500 ft
3ra Avenida Norte # 20A
Healing Hands Therapy Spa
1500 ft
Restaurants
7 Caldos
100 ft
Calle Oriente 3a
Arrin Cuan Antigua
200 ft
Callejon Concepcion Casa #2
Samsara's Garden
700 ft
6 Street West # 33 Interior
Akai Sushi & Oriental
500 ft
4a Calle Oriente No. 39
Romeo y Julieta Guatemala
600 ft
4a Calle Oriente 39 100m from Morjan gas station
El Convento
1700 ft
2 Avenida Norte No. 11
Welten
1100 ft
4a Calle Oriente No. 21
Bistrot Cinq
1300 ft
4 a Calle Oriente # 7 Centro Histórico
La Casa del Ron
1300 ft
4 Calle Oriente # 22 Salida Hacia la Capital
Explore Antigua
Explore The Best Of Antigua
Top Attractions
Activities
Dining
Entertainment
ChocoMuseo
ChocoMuseo
6 minutes walking
Chocolate museum featuring tastings and workshops. Experience the history and process of chocolate making.
Casa Santo Domingo Museums
Casa Santo Domingo Museums
7 minutes walking
A collection of museums showcasing local art and history set in a former convent. Unique architecture and exhibits await.
Cerro de La Cruz
Cerro de La Cruz
15 minutes walking
Scenic viewpoint offering panoramic views of Antigua. A perfect spot for photography and appreciating the landscape.
Central Park
Central Park
9 minutes walking
A central gathering place surrounded by historical buildings. Ideal for relaxation, people-watching, and cultural encounters.
Hiking at Cerro de La Cruz
15 minutes walking
Hiking trail leading to stunning views of Antigua. Suitable for various skill levels, great for nature lovers.
Spa Treatments at Casa Santo Domingo
7 minutes walking
Relaxation and wellness treatments available onsite. Ideal for unwinding after a day of exploration.
Visit Local Markets
9 minutes walking
Local markets offering handcrafted goods and traditional foods. Immerse in the local culture and enjoy vibrant atmospheres.
7 Caldos
7 Caldos
1 minute walking
Local cuisine with a cozy atmosphere. Famous for its hearty soups and traditional Guatemalan dishes.
Romeo y Julieta Guatemala
Romeo y Julieta Guatemala
3 minutes walking
Italian restaurant with a romantic vibe. Known for its authentic pasta and wood-fired pizzas.
Samsara's Garden
Samsara's Garden
3 minutes walking
An open-air dining experience focusing on organic and seasonal ingredients. Vegetarian options available.
Belfinart
Belfinart
10 minutes walking
Art gallery hosting local exhibitions. Perfect for art lovers seeking inspiration and cultural experiences.
Live Music at La Taberna
9 minutes walking
A lively venue featuring local bands. Enjoy typical drinks and music, creating a vibrant nightlife experience.
Getting around
City Centre
Antigua12 min  ·  3300 ft
Airports
La Aurora International Airport (GUA)55 min  ·  22.5 mi
Interested in Exclusive Early Booking Rates?
Take advantage of special rates!
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Private parking is possible on site for free.
Internet
is available in public areas for free.
Breakfast
The hotel offers a full breakfast at the price of US$22 per person per day. 
Children & extra beds
There are no extra beds provided in a room. 
Pets
Pets are allowed on request.
Number of rooms:
128
FAQs
About Hotel Museo Spa Casa Santo Domingo
What is the check-in and check-out policy at Hotel Museo Spa Casa Santo Domingo?
Check-in is at 15:00 and check-out is by 12:00.
How far is Hotel Museo Spa Casa Santo Domingo from La Aurora Airport?
The hotel is 40 km from La Aurora Airport, which takes approximately 45 minutes by car.
What are some nearby attractions to Hotel Museo Spa Casa Santo Domingo?
Nearby attractions include Santa Catalina Arch (0.5 km), Central Park (0.5 km), and Cerro de La Cruz (1 km).
What dining options are available at Hotel Museo Spa Casa Santo Domingo?
Guests can enjoy gastronomic experiences at El Refectorio and Al Tenedor del Cerro, featuring international cuisine.
Does Hotel Museo Spa Casa Santo Domingo offer access to a fitness center?
The hotel features a fully equipped fitness center for guest use.
Is parking available at Hotel Museo Spa Casa Santo Domingo?
Complimentary private parking is available on-site without the need for a reservation.
What amenities can guests expect in their rooms at Hotel Museo Spa Casa Santo Domingo?
Rooms include air conditioning, flat-screen TVs, and tea/coffee making facilities.
Does Hotel Museo Spa Casa Santo Domingo provide any business amenities?
The hotel offers meeting rooms and conference facilities suitable for business events.
Are there children-friendly options at Hotel Museo Spa Casa Santo Domingo?
The hotel offers children's services, including special amenities in rooms for ages 12 to 17, with parent supervision required.
What amenities does Hotel Museo Spa Casa Santo Domingo offer for relaxation?
The hotel provides an outdoor swimming pool, jacuzzis, and wet and dry saunas.
What type of hotel is Hotel Museo Spa Casa Santo Domingo?
It is a historic spa hotel that integrates art and culture within its unique setting.

Next best alternative

Consider them for your next trip.
Check-in
25Jan2026Select date
Check-out
26Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near Hotel Museo Spa Casa Santo Domingo
El Convento Boutique Hotel Antigua Exterior photo
Mobile-only price

El Convento Boutique Hotel Antigua

9.2
Perfect730 reviews
284m from property
USD 234USD 210
per night
Villa Las Mil Flores Antigua Interior photo
Mobile-only price

Villa Las Mil Flores Antigua

10.0
Perfect25 reviews
289m from property
USD 229USD 206
per night
Casa Faustina Boutique Hotel Antigua Interior photo
Mobile-only price

Casa Faustina Boutique Hotel Antigua

8.9
Great163 reviews
396m from property
USD 121USD 108
per night