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From143US$ /night
Check-in
10Dec2025Select date
Check-out
11Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Close to the Gateway Arch
Perfect
8.4
8.9
/10
4.2
4.2
/5

The 4-star 21C Museum Hotel St Louis Saint Louis provides proximity to Inside the Economy Museum at the Federal Reserve Bank, which is located merely 0.8 miles away. Featuring an indoor pool along with an à la carte restaurant, the contemporary hotel offers a setting a mere 7 minutes by foot from City Museum.

Location

This hotel is located in the center of Saint Louis, within convenient reach of Campbell House Museum. Cardinals Hall of Fame and Museum is around 1 mile from the boutique 21C Museum Hotel St Louis Saint Louis, and Lambert airport is 16 miles away.

The Saint Louis property is situated a walk from Busch Stadium, and Civic Center Transit Center bus station lies just a 10-minute walk away.

Union train station can be found only 0.6 miles from 21C Museum Hotel St Louis.

Rooms

The smoke-free 21C Museum Hotel St Louis welcomes guests to 173 non-smoking rooms. Some of them come with Wi-Fi and a TV along with coffee/tea making equipment. The nice touches include a stone fireplace, along with a cabinet. Offering a bathtub, a walk-in shower, and a separate toilet, the bathrooms are also appointed with a hairdryer and bathrobes.

Eat & Drink

Idol Wolf restaurant serves Spanish cuisine for dinner. Guests can relax in the on-site lounge bar.

Leisure & Business

This Saint Louis hotel includes a fitness studio, a spa salon to ensure guests maximum relaxation. Corporate travelers will benefit from a meeting room available on site.

Must-do experiences

  • Visit the City Museum for an interactive St. Louis history experience.
  • Try a classic toasted ravioli at the Pasta House Co. nearby.
  • Discover the vibrant art scene at the Contemporary Art Museum.
  • Take a stroll through Forest Park for stunning scenery and free activities.
  • Don't miss the impressive Gateway Arch for breathtaking views of the city.
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
47 m² 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
40 m² 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
29 m² 
1 King-size bed
Shower
Heating
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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
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Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
Explore Saint Louis
Explore St. Louis
Top Attractions
Activities
Dining
Entertainment
Campbell House Museum
Campbell House Museum
2 minutes' walk
Historic house museum showcasing 19th-century opulence. Offers guided tours detailing the family's life and art collection.
City Museum
City Museum
7 minutes' walk
Unique blend of playground, funhouse, and enchanting vintage architecture, offering creativity and adventure for all ages.
The Gateway Arch
The Gateway Arch
25 minutes' walk
Iconic monument representing westward expansion. Features an observation deck with stunning city views and a visitor center.
Stifel Theatre
Stifel Theatre
8 minutes' walk
Beautifully restored venue hosting concerts, comedy shows, and live performances, offering an unforgettable cultural experience.
Malcolm W Martin Memorial Park
8 minutes' drive
Large urban park featuring walking trails, beautiful views of the Arch, and picnic spots for relaxation and outdoor fun.
Biking the Riverfront Trails
8 minutes' drive
Scenic trails along the Mississippi River ideal for cycling enthusiasts. Rentals available nearby for easy access.
The Last Kitchen
The Last Kitchen
5 minutes' walk
Casual eatery serving American comfort food with a modern twist. Known for burgers, salads, and craft beers.
Rooftop Cafe at City Museum
Rooftop Cafe at City Museum
5 minutes' walk
Charming rooftop setting with spectacular views. Offers a seasonal menu featuring local ingredients and fun snacks.
Kiener Plaza
Kiener Plaza
8 minutes' walk
Vibrant public space hosting events, concerts, and a seasonal ice rink, providing enjoyment for families and visitors alike.
National Blues Museum
National Blues Museum
16 minutes' walk
Museum dedicated to the history and impact of blues music, featuring interactive exhibits and live performances.
Getting around
City Centre
Saint Louis8 min  ·  600 m
Airports
Lambert (STL)33 min  ·  21.8 km
MidAmerica St. Louis/Scott Air Force Base (BLV)62 min  ·  40.8 km
Train
Union Station9 min  ·  700 m
Bus
Bus stop3 min  ·  200 m
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137
FAQs
About 21C Museum Hotel St Louis
What is the distance from 21C Museum Hotel St Louis to St Louis Lambert International Airport?
21C Museum Hotel St Louis is located 21 km from St Louis Lambert International Airport.
What popular attractions are near 21C Museum Hotel St Louis?
Nearby attractions include the Gateway Arch (3 km), Old Courthouse (2 km), and City Museum (0.5 km).
What dining options are available at 21C Museum Hotel St Louis?
The hotel features an on-site restaurant serving Spanish cuisine and has a bar/lounge area.
Is breakfast served at 21C Museum Hotel St Louis?
An American breakfast is available at 21C Museum Hotel St Louis.
What fitness amenities are provided at 21C Museum Hotel St Louis?
Guests have access to a fitness center, indoor swimming pool, hot tub, and wellness spa.
What amenities are included in the rooms at 21C Museum Hotel St Louis?
Rooms feature air conditioning, a flat-screen TV with cable channels, a seating area, a safety deposit box, and a private bathroom.
What hygiene and safety measures are taken at 21C Museum Hotel St Louis?
The hotel provides 24-hour security and luggage storage for guests.
What are the check-in and check-out times at 21C Museum Hotel St Louis?
Check-in is at 16:00 and check-out is at 11:00.
Is parking available at 21C Museum Hotel St Louis?
Valet parking services are available for guests at 21C Museum Hotel St Louis.
Does 21C Museum Hotel St Louis offer any special facilities for events?
The hotel provides meeting and event spaces with advanced AV technology.
What entertainment or activities does 21C Museum Hotel St Louis provide?
On-site activities include billiards, a games room, and temporary art galleries.
What services does 21C Museum Hotel St Louis offer for business travelers?
The hotel offers a business center and meeting facilities for corporate groups.

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Check-in
10Dec2025Select date
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Rooms and Guests2 Guests, 1 Room

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21C Museum Hotel St Louis

8.4
Great913 reviews
600 m from center
129 US$
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