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From163US$ /night
Check-in
10Mar2026Select date
Check-out
11Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Close to the Gateway Arch
Great
8.5
8.8
/10
4.2
4.1
/5

Rooms & Suites

21C Museum Hotel St Louis offers art-filled rooms and suites designed for rest and inspiration. The Luxury King Suite includes a separate living area, soaking tub, and expansive windows, while the two-story 21c King Suite features a personal fitness loft and large living space. Accommodations include original artwork by Missouri-based artists and premium in-room amenities.

Dining

Idol Wolf, the hotel's on-site restaurant, combines local ingredients with classic Spanish gastronomy in a tapas style. Guests can experience a diverse culinary journey inspired by both Iberian traditions and Midwestern flavors. In-room dining options are also available, ensuring guests have access to chef-driven meals anytime.

Wellness

The Locust Street Athletic and Swim Club provides a holistic approach to fitness and wellness. This facility offers personal and group training sessions, spa services, and a historic four-lane lap pool. Guests also have access to sauna and steam rooms, creating a comprehensive wellness experience.

Location

21C Museum Hotel St Louis is located downtown, presenting easy access to major attractions like Busch Stadium and the City Museum. This central position allows visitors to explore the vibrant cultural landscape of St Louis. The hotel's connection to local businesses enriches the experience of guests with authentic, regionally inspired offerings.

Community Impact

The hotel engages with local nonprofits each month through its Community Love program, fostering connections and supporting local causes. Other initiatives include hosting Coffee Talks, which promote conversations about social impact. Such efforts are integral to 21C St Louis, promoting innovation and collaboration in the community.

Highlights

Location: Downtown St Louis near major attractions .

Dining: On-site dining at Idol Wolf .

Wellness: Locust Street Athletic and Swim Club with spa services .

Art: Permanent art installations by contemporary artists .

Must-do experiences

  • Visit the City Museum for an interactive St. Louis history experience.
  • Try a classic toasted ravioli at the Pasta House Co. nearby.
  • Discover the vibrant art scene at the Contemporary Art Museum.
  • Take a stroll through Forest Park for stunning scenery and free activities.
  • Don't miss the impressive Gateway Arch for breathtaking views of the city.
View all

Select your room type

21C Museum Hotel St Louis offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Deluxe King Room
2 persons
315 sq. feet 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
510 sq. feet 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
435 sq. feet 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
315 sq. feet 
1 King-size bed
Shower
Heating
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Facilities

21C Museum Hotel St Louis offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.9/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
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21C Museum Hotel St Louis Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
1800 ft
Museum
Campbell House Museum
300 ft
Church
Christ Church Cathedral
1500 ft
1315 Chestnut St
Soldiers Memorial Military Museum
2000 ft
Aquarium
World Aquarium
1400 ft
Church
Centenary United Methodist Church
700 ft
Night club
The Boom Boom Room
1000 ft
13th and Locust
Lucas Garden Park
1200 ft
Restaurants
The Last Kitchen
1200 ft
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
1100 ft
1330 Washington Ave
Nara Cafe and Hookah Lounge
1100 ft
1326 Washington Ave
Flannery's
1300 ft
1324 Washington Ave
Rooftop Cafe at City Museum
1400 ft
701 N 15th St Fl 11
Lucas Park Grille
1500 ft
1234 Washington Avenue
Rosalita's Cantina
1600 ft
1235 Washington Avenue
Blondie's Coffee
1500 ft
1301 Washington Ave
Imo's Pizza
1400 ft
1828 Washington Ave
Papa John's Pizza
2100 ft
201 N Tucker Blvd Ste E
Bootleggin' BBQ
2200 ft
1933 Washington Ave
Explore Saint Louis
Explore St. Louis
Top Attractions
Activities
Dining
Entertainment
Campbell House Museum
Campbell House Museum
2 minutes' walk
Historic house museum showcasing 19th-century opulence. Offers guided tours detailing the family's life and art collection.
City Museum
City Museum
7 minutes' walk
Unique blend of playground, funhouse, and enchanting vintage architecture, offering creativity and adventure for all ages.
The Gateway Arch
The Gateway Arch
25 minutes' walk
Iconic monument representing westward expansion. Features an observation deck with stunning city views and a visitor center.
Stifel Theatre
Stifel Theatre
8 minutes' walk
Beautifully restored venue hosting concerts, comedy shows, and live performances, offering an unforgettable cultural experience.
Malcolm W Martin Memorial Park
8 minutes' drive
Large urban park featuring walking trails, beautiful views of the Arch, and picnic spots for relaxation and outdoor fun.
Biking the Riverfront Trails
8 minutes' drive
Scenic trails along the Mississippi River ideal for cycling enthusiasts. Rentals available nearby for easy access.
The Last Kitchen
The Last Kitchen
5 minutes' walk
Casual eatery serving American comfort food with a modern twist. Known for burgers, salads, and craft beers.
Rooftop Cafe at City Museum
Rooftop Cafe at City Museum
5 minutes' walk
Charming rooftop setting with spectacular views. Offers a seasonal menu featuring local ingredients and fun snacks.
Kiener Plaza
Kiener Plaza
8 minutes' walk
Vibrant public space hosting events, concerts, and a seasonal ice rink, providing enjoyment for families and visitors alike.
National Blues Museum
National Blues Museum
16 minutes' walk
Museum dedicated to the history and impact of blues music, featuring interactive exhibits and live performances.
Getting around
City Centre
Saint Louis8 min  ·  2000 ft
Airports
St. Louis Lambert International Airport (STL)33 min  ·  13.5 mi
Belleville, IL (BLV)62 min  ·  25.4 mi
Train
Union Station9 min  ·  2300 ft
Bus
Bus stop3 min  ·  700 ft
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137

Reviews and Ratings

Feedback about 21C Museum Hotel St Louis from previous guests about their experience.
Review score
Based on 1115 verified reviews
8.5/10
Great
83%
Recommend
Breakfast
6.6/10
Cleanliness
8.9/10
Comfort
8.9/10
Facilities
8.9/10
Free Wi-Fi
7.8/10
Location
8.5/10
Paid Wi-Fi
6.0/10
Staff
8.7/10
Value for money
8.2/10
Pros
Art museum
Spacious rooms
Nice pool
Cons
Parking issues
Slow service
Guest reviews
based on 964 reviews
8.5/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
FAQs
About 21C Museum Hotel St Louis
What is the distance from 21C Museum Hotel St Louis to St Louis Lambert International Airport?
21C Museum Hotel St Louis is located 21 km from St Louis Lambert International Airport.
What popular attractions are near 21C Museum Hotel St Louis?
Nearby attractions include the Gateway Arch (3 km), Old Courthouse (2 km), and City Museum (0.5 km).
What dining options are available at 21C Museum Hotel St Louis?
The hotel features an on-site restaurant serving Spanish cuisine and has a bar/lounge area.
Is breakfast served at 21C Museum Hotel St Louis?
An American breakfast is available at 21C Museum Hotel St Louis.
What fitness amenities are provided at 21C Museum Hotel St Louis?
Guests have access to a fitness center, indoor swimming pool, hot tub, and wellness spa.
What amenities are included in the rooms at 21C Museum Hotel St Louis?
Rooms feature air conditioning, a flat-screen TV with cable channels, a seating area, a safety deposit box, and a private bathroom.
What hygiene and safety measures are taken at 21C Museum Hotel St Louis?
The hotel provides 24-hour security and luggage storage for guests.
What are the check-in and check-out times at 21C Museum Hotel St Louis?
Check-in is at 16:00 and check-out is at 11:00.
Is parking available at 21C Museum Hotel St Louis?
Valet parking services are available for guests at 21C Museum Hotel St Louis.
Does 21C Museum Hotel St Louis offer any special facilities for events?
The hotel provides meeting and event spaces with advanced AV technology.
What entertainment or activities does 21C Museum Hotel St Louis provide?
On-site activities include billiards, a games room, and temporary art galleries.
What services does 21C Museum Hotel St Louis offer for business travelers?
The hotel offers a business center and meeting facilities for corporate groups.

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